Methyl 4'-fluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylate → 2-Allyloxy-5-(4'-fluorophenyl)-benzoic acid

HRID 442276Notes

Reaction equation

HRID 442276 reaction equation
O[C:2]1[CH:10]=CC=C[C:3]=1C([O-])=O.C[O:12][C:13](=[O:28])[C:14]1[CH:19]=[C:18]([C:20]2[CH:25]=[CH:24][C:23]([F:26])=[CH:22][CH:21]=2)[CH:17]=[CH:16][C:15]=1[OH:27]>>[CH2:10]([O:27][C:15]1[CH:16]=[CH:17][C:18]([C:20]2[CH:25]=[CH:24][C:23]([F:26])=[CH:22][CH:21]=2)=[CH:19][C:14]=1[C:13]([OH:12])=[O:28])[CH:2]=[CH2:3]

Participants

3

Reactant 2

HCID 21416429Methyl 4'-fluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylateHCID 178524311Salicylate

Product 1

HCID 214164462-Allyloxy-5-(4'-fluorophenyl)-benzoic acid

Procedure

When the 2-hydroxy-benzoate compounds obtained from Example 9 are used in place of methyl-2-hydroxy-5-(4'-fluorophenyl)-benzoate in the above example, there are obtained the corresponding allyloxy-benzoic acid compounds.

Sources & evidence

ORD record
ord-57bdfddf6fbf47138a0ae11c41b08947
Source dataset
uspto-grants-1977_08
Patent number
US04044049

Reaction notes

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