HCID 21414407, compound → HCID 21414391, compound

HRID 442383Notes

Reaction equation

HRID 442383 reaction equation
[Cl:1][C:2]1[CH:24]=[CH:23][C:5]([N:6]([C:8]2[CH:22]=[CH:21][CH:20]=[CH:19][C:9]=2[NH:10][C:11](=O)[CH:12]2[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]2)[CH3:7])=[CH:4][CH:3]=1.C(N1CCC(C(NC2C=CC=CC=2)=O)CC1)(OCC1C=CC=CC=1)=O>>[Cl:1][C:2]1[CH:24]=[CH:23][C:5]2[N:6]([CH3:7])[C:8]3[CH:22]=[CH:21][CH:20]=[CH:19][C:9]=3[N:10]=[C:11]([CH:12]3[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]3)[C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 21414407HCID 21414407, compoundHCID 21414421HCID 21414421, compound

Product 1

HCID 21414391HCID 21414391, compound

Procedure

The compound 2'-(p-chloro-N-methylanilino)isonipecotanilide, prepared by hydrolysis of the corresponding 1-carbobenzoxyisonipecotanilide, is cyclized by the procedure of Example 1 and, after isolation and purification of the product, 2-chloro-5-methyl-11-(4-piperidyl)-5H-dibenzo[b,e][1,4]-diazepine is thereby obtained.

Workup

  1. customafter isolation and purification of the product, 2-chloro-5-methyl-11-(4-piperidyl)-5H-dibenzo[b,e][1,4]-diazepine
  2. customis thereby obtained

Sources & evidence

ORD record
ord-9bb989286de04984a73b4ac9b24bf724
Source dataset
uspto-grants-1977_08
Patent number
US04045445

Reaction notes

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