HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → HCID 136409731, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 21414377 | HCID 21414377 | — |
| Product | HCID 136409731 | HCID 136409731 | — |
Reaction Steps
The general procedures of Example 6 are repeated. The compound o-(4-fluoro-2-nitroanilino)phenyl 1-methyl-4-piperidyl ketone is reduced and cyclized with phosphorus oxychloride to give 8-fluoro-11-(1-methyl-4-piperidyl)-5H-dibenzo[b,e][1,4]diazepine base, which is converted to the fumarate salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04045445 |
| Source dataset | uspto-grants-1977_08 |
| ORD ID | ord-c8195fd8beca432d8be374859426fe57 |
| Source note | uspto-grants-1977_08 |