反应详情

温度

185 °C

A stirred slurry of 66 g. (0.5 mole) of aluminum chloride and 42.5 g. (0.3 mole) of benzoyl chloride was heated to 150° C. and then 133 g. (0.1 mole) of indolin-2-one was slowly added at a rate so that the temperature of the stirred reaction mixture was maintained at 180°-185° C. After addition the reaction mixture was stirred for five minutes at 185° C., cooled and poured into ice water. The 5-benzoylindolin-2-one which precipitated was collected and recrystallized from methanol; it melted at 204°-205° C. The yield was 17.5 g. (73%).

1. temperaturewas maintained at 180°-185° C
2. additionAfter addition the reaction mixture
3. temperaturecooled
4. customThe 5-benzoylindolin-2-one which precipitated
5. customwas collected
6. customrecrystallized from methanol