HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 11572316, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1,2,3,6-Tetrahydropyridine | HCID 12750 | — |
| Reactant | Pivaloyl chloride | HCID 62493 | — |
| Reactant | 1,4-Benzodioxane-6-carboxylic Acid | HCID 2758833 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 11572316 | HCID 11572316 | — |
Reaction Steps
1,4-benzodioxan-6-carboxylic acid (3.0 g; 16.7 mmol) was suspended in 40 mL of dichloromethane. The acid dissolved upon addition of 3.7 g (2.2 equivalents) of triethylamine. Addition of 2.0 g of pivaloyl chloride was exothermic, and produced a dense precipitate. The mixture was stirred at room temperature for about 20 minutes, then 1.52 g of 1,2,3,6-tetrahydropyridine was slowly added.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05891876 |
| Source dataset | uspto-grants-1999_04 |
| ORD ID | ord-315dddebf6ea48c5a058cfc7901b3226 |
| Source note | uspto-grants-1999_04 |