HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dichlorobenzaldehyde → (3Z)-1-acetyl-3-(2,6-dichlorobenzylidene)-2,5-piperazinedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dichlorobenzaldehyde | HCID 6737 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1,4-Diacetyl-2,5-piperazinedione | HCID 540371 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | (3Z)-1-acetyl-3-(2,6-dichlorobenzylidene)-2,5-piperazinedione | HCID 21308865 | 40% |
Reaction Steps
1,4-Diacetyl-2,5-piperazinedione prepared by the published procedure mentioned in Reference Example 3, was stirred in DMF with 2,6-dichlorobenzaldehyde and triethylamine and heated to 120°-130° C. for 1-3 h. The title compound was obtained with a yield of 40%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05891877 |
| Source dataset | uspto-grants-1999_04 |
| ORD ID | ord-580416b22eb44c648a525512ce786adc |
| Source note | uspto-grants-1999_04 |