HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylbenzoyl Chloride → Methyl 2-(4-Methylbenzoyl)-4,5-methylenedioxyphenylacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylbenzoyl Chloride | HCID 13405 | — |
| Reactant | Methyl 2-(1,3-dioxaindan-5-yl)acetate | HCID 266588 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Tin tetrachloride | HCID 24287 | — |
| Product | Methyl 2-(4-Methylbenzoyl)-4,5-methylenedioxyphenylacetate | HCID 10710218 | — |
Reaction Steps
The title compound was prepared from methyl 3,4-methylenedioxyphenylacetate (319 mg, 1.64 mmol) in CH2Cl2 (5 mL), SnCl4 (1.0M solution in CH2Cl2 ; 3.5 mL mmol) and 4-toluoyl chloride (260 μL, 1.97 mmol) as an oily solid (90 mg, 18%). 1H NMR (CDCl3) 7.69 (d, 2H, J=8.0), 7.24 (d, 2H, J=8.0), 6.88 (s, 1H), 6.83 (s, (s, 2H), 3.78 (s, 2H), 3.60 (s, 3H), 2.43 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05891871 |
| Source dataset | uspto-grants-1999_04 |
| ORD ID | ord-7b5b635c632d4fbd8c5bd5e452170df8 |
| Source note | uspto-grants-1999_04 |