HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Anisoyl chloride → Methyl 2-(4-Methoxybenzoyl)-4,5-methylenedioxyphenylacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Anisoyl chloride | HCID 7477 | — |
| Reactant | Tin tetrachloride | HCID 24287 | — |
| Reactant | Methyl 2-(1,3-dioxaindan-5-yl)acetate | HCID 266588 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Methyl 2-(4-Methoxybenzoyl)-4,5-methylenedioxyphenylacetate | HCID 10735027 | — |
Reaction Steps
The title compound was prepared from methyl 3,4-methylenedioxyphenylacetate (244 mg, 1.26 mmol) in CH2Cl2 (5 mL), SnCl4 (1.0M solution in CH2Cl2 ; 2.5 mL 2.5 mmol) and 4-anisoyl chloride (220 μL, 1.62 mmol) as a white solid (110 mg, 27%). 1H NMR (CDCl3) 7.78 (d, 2H, J=8.6), 6.93 (d, 2H, J=8.6), 6.86 (s, 1H), 6.83 (s, 1H), 6.03 (s, 2H), 3.88 (s, 3H), 3.75 (s, 2H), 3.59 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05891871 |
| Source dataset | uspto-grants-1999_04 |
| ORD ID | ord-000364a43b5641a4865807beb0d31316 |
| Source note | uspto-grants-1999_04 |