HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methylsulphanyl-5-(2-oxo-oxazolidin-3-ylmethyl)-1,3-dihydro-indol-2-one → 5-(2-Oxo-oxazolidin-3-ylmethyl)-1,3-dihydro-indol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methylsulphanyl-5-(2-oxo-oxazolidin-3-ylmethyl)-1,3-dihydro-indol-2-one | HCID 66636411 | — |
| Catalyst | Zinc | HCID 23994 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 5-(2-Oxo-oxazolidin-3-ylmethyl)-1,3-dihydro-indol-2-one | HCID 66636156 | — |
Reaction Steps
To a solution of the compound obtained in Step C in glacial acetic acid (320 ml) there is added powdered zinc (1 mol). The reaction mixture is stirred overnight at ambient temperature and is then filtered. The filtrate is concentrated, and then 100 ml of water are added. The solid formed is filtered off and then recrystallised from ethanol to yield the title product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08541412B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-f89c040419044358a9f0db32a303f682 |
| Source note | uspto-grants-2013_09 |