HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → HCID 21999006, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 1-Methyl-6-(methylthio)-1H-indole | HCID 53996658 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 21999006 | HCID 21999006 | 82.5% |
Reaction Steps
To a solution of 1-methyl-6-methylsulfanyl-1H-indole (658 mg, 3.71 mmol) in Et2O(7 ml) at 0° C., was added oxalyl chloride (0.55 ml, 6.31 mmol). After stirring for 3 hours, the orange solid was collected, washed with Et2O, and dried to afford (1-methyl-6-methylsulfanyl-1H-indol-3-yl)-oxo-acetyl chloride (819 mg, 66%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05891901 |
| Source dataset | uspto-grants-1999_04 |
| ORD ID | ord-c940c13e679e4ada9ce3b292c0f94196 |
| Source note | uspto-grants-1999_04 |