Dimethylformamide → HCID 18796830, compound

Participants

Reaction Steps

To 2-chloro-3-cyano-5-methoxypyridine (0.53 g) and methyl thioglycolate (280 μL) in DMF (10 mL) at 5° C. was added a 1.0M solution of KOtBu/THF (3.8 mL). The reaction was stirred 20 min at 5°, then 2 h at RT, quenched in sat'd NH4Cl, the solid precipitate was collected, washed with water and dried to give 0.53 g (71%) of the title compound.

Provenance & Evidence