Sodium Hydroxide → HCID 53832874, compound

HRID 442808Notes

Reaction equation

HRID 442808 reaction equation
[CH2:1]([O:3][P:4]([C:9]1[CH:14]=[CH:13][C:12]([C:15]2([CH2:22][CH:23]3[C:36]4[CH:35]=[CH:34][CH:33]=[CH:32][C:31]=4[O:30][C:29]4[C:24]3=[CH:25][CH:26]=[CH:27][CH:28]=4)[NH:19]C(=O)N[C:16]2=[O:21])=[CH:11][CH:10]=1)([O:6][CH2:7][CH3:8])=[O:5])[CH3:2].[OH-:37].[Na+]>O>[NH2:19][C:15]([C:12]1[CH:13]=[CH:14][C:9]([P:4]([O:3][CH2:1][CH3:2])([O:6][CH2:7][CH3:8])=[O:5])=[CH:10][CH:11]=1)([CH2:22][CH:23]1[C:36]2[CH:35]=[CH:34][CH:33]=[CH:32][C:31]=2[O:30][C:29]2[C:24]1=[CH:25][CH:26]=[CH:27][CH:28]=2)[C:16]([OH:37])=[O:21]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 53795061HCID 53795061, compound

Product 1

HCID 53832874HCID 53832874, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

5-(4-Diethylphosphonophenyl)-5-(9H-xanthen-9-ylmethyl)hydantoin (1.0 g), 2.0 mmol) was reacted with aqueous sodium hydroxide (2M, 6 ml) in water (4 ml) following the procedure described in Example 1 (vi) to give 2-amino-3-(9H-xanthen-9-yl)-2-(4-diethylphosphonophenyl)propanoic acid as a white powder.

Sources & evidence

ORD record
ord-fd819de93be64744a94b53792094f88f
Source dataset
uspto-grants-1999_04
Patent number
US05891899

Reaction notes

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