HRID442853

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID69768

p,p'-Dimethoxybenzhydryl alcohol

C15H16O3

结构：O=C(c1cc2ccccc2[nH]1)N1CCN(c2ccccc2Cl)CC1

HCID17877334

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(C(c2ccc(OC)cc2)c2c(C(=O)N3CCN(c4ccccc4Cl)CC3)[nH]c3ccccc23)cc1

HCID70147134

未命名化合物

收率 81%

PROCEDURE

实验过程

Substantially the same procedure as in Example 1 was repeated using 4,4'-dimethoxybenzhydrol (2.37 g, 9.71 mmol) and 1-(2-chlorophenyl)-4-(indol-2-ylcarbonyl)piperazine (3.0 g, 8.83 mmol) to give 4.0 g (yield: 81%) of the title compound.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-401994d8d4114afb9a0596f68bea4091
来源数据集: uspto-grants-1999_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05891902
来源说明: uspto-grants-1999_04

反应 SMILES

[CH3:1][O:2][C:3]1[CH:18]=[CH:17][C:6]([CH:7](O)[C:8]2[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[CH:10][CH:9]=2)=[CH:5][CH:4]=1.[Cl:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[N:26]1[CH2:31][CH2:30][N:29]([C:32]([C:34]2[NH:35][C:36]3[C:41]([CH:42]=2)=[CH:40][CH:39]=[CH:38][CH:37]=3)=[O:33])[CH2:28][CH2:27]1>>[CH3:1][O:2][C:3]1[CH:18]=[CH:17][C:6]([CH:7]([C:8]2[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[CH:10][CH:9]=2)[C:42]2[C:41]3[C:36](=[CH:37][CH:38]=[CH:39][CH:40]=3)[NH:35][C:34]=2[C:32]([N:29]2[CH2:28][CH2:27][N:26]([C:21]3[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=3[Cl:19])[CH2:31][CH2:30]2)=[O:33])=[CH:5][CH:4]=1