HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1) → 2-[4-(2-Chlorophenyl)piperazinylcarbonyl]-3-(diphenylmethyl)-1-(2-morpholinoethyl)indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1) | HCID 77210 | — |
| Reactant | HCID 15858911 | HCID 15858911 | — |
| Product | 2-[4-(2-Chlorophenyl)piperazinylcarbonyl]-3-(diphenylmethyl)-1-(2-morpholinoethyl)indole | HCID 15858912 | 74.2% |
Reaction Steps
Substantially the same procedure as in Example 89 was repeated using Compound 88 (1.0 g, 1.98 mmol) obtained in Example 88 and 2-morpholinoethylchloride hydrochloride (385 mg, 2.07 mmol) to give 0.91 g (yield: 74%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05891902 |
| Source dataset | uspto-grants-1999_04 |
| ORD ID | ord-4d5042a482e44ccbb1c9936e2d443da2 |
| Source note | uspto-grants-1999_04 |