N,N-Dimethylaminoethyl chloride hydrochloride → HCID 67692092, compound

HRID 442868Notes

Reaction equation

HRID 442868 reaction equation
[CH3:1][O:2][CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([CH:11]([C:30]2[CH:35]=[CH:34][C:33]([O:36][CH2:37][O:38][CH3:39])=[CH:32][CH:31]=2)[C:12]2[C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[NH:14][C:13]=2[S:21]([N:24]2[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]2)(=[O:23])=[O:22])=[CH:7][CH:6]=1.Cl.[CH3:41][N:42]([CH3:46])[CH2:43][CH2:44]Cl>>[CH3:1][O:2][CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([CH:11]([C:30]2[CH:35]=[CH:34][C:33]([O:36][CH2:37][O:38][CH3:39])=[CH:32][CH:31]=2)[C:12]2[C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[N:14]([CH2:44][CH2:43][N:42]([CH3:46])[CH3:41])[C:13]=2[S:21]([N:24]2[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29]2)(=[O:22])=[O:23])=[CH:7][CH:6]=1

Participants

3

Reactant 2

HCID 11636816N,N-Dimethylaminoethyl chloride hydrochlorideHCID 67691518HCID 67691518, compound

Product 1

HCID 67692092HCID 67692092, compoundYield 74%

Procedure

Substantially the same procedure as in Example 243 was repeated using Compound 244 (1.32 g, 2.40 mmol) obtained in Example 245 and 2-dimethylaminoethylchloride hydrochloride (345 mg, 2.40 mmol) to give 1.1 g (yield: 74%) of the title compound.

Sources & evidence

ORD record
ord-db8374062705405496060abb1c472eb7
Source dataset
uspto-grants-1999_04
Patent number
US05891902

Reaction notes

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