Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 442875Generated: October 25, 2026

4,4'-Difluorobenzhydryl alcohol → N-Isopropyl-3-[bis(4-fluorophenyl)methyl]indole-2-sulfonamide

https://huagongshe.com/reaction/442875

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4,4'-Difluorobenzhydryl alcoholHCID 123049—
ReactantN-isopropylindole-2-sulfonamideHCID 54122335—
ProductN-Isopropyl-3-[bis(4-fluorophenyl)methyl]indole-2-sulfonamideHCID 6759558980%

Reaction Steps

Substantially the same procedure as in Example 266 was repeated using 4,4'-difluorobenzhydrol (0.99 g, 4.50 mmol) and N-isopropylindole-2-sulfonamide (1.00 g, 4.46 mmol) to give 1.56 g (yield: 80%) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05891902
Source datasetuspto-grants-1999_04
ORD IDord-e3974e13e19d48069c8ea0859610e2d1
Source noteuspto-grants-1999_04