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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 442884Generated: October 30, 2026

Ethyl indole-2-carboxylate → Ethyl 3-(4-benzyloxybenzhydryl)indole-2-carboxylate

https://huagongshe.com/reaction/442884

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl indole-2-carboxylateHCID 73125—
Reactant4-BenzyloxybenzhydrolHCID 10589580—
ProductEthyl 3-(4-benzyloxybenzhydryl)indole-2-carboxylateHCID 5450853095%

Reaction Steps

Substantially the same procedure as in Reference Example 4 was repeated using 4-benzyloxybenzhydrol (30.0 g, 103 mmol) and ethyl indole-2-carboxylate (18.5 g, 97.9 mmol) to give 42.7 g (yield: 95%) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05891902
Source datasetuspto-grants-1999_04
ORD IDord-0529c54903954bfd8c50eca480c339c6
Source noteuspto-grants-1999_04