HCID 6619014, compound → HCID 67594329, compound

HRID 442887Notes

Reaction equation

HRID 442887 reaction equation
[Cl:1][CH2:2][CH2:3][O:4][C:5]1[CH:18]=[CH:17][C:8]([CH:9](O)[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:7][CH:6]=1.[CH3:19][N:20]([CH3:37])[CH2:21][CH2:22][N:23]1[C:31]2[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=2)[CH:25]=[C:24]1[C:32]([O:34][CH2:35][CH3:36])=[O:33]>>[Cl:1][CH2:2][CH2:3][O:4][C:5]1[CH:18]=[CH:17][C:8]([CH:9]([C:25]2[C:26]3[C:31](=[CH:30][CH:29]=[CH:28][CH:27]=3)[N:23]([CH2:22][CH2:21][N:20]([CH3:37])[CH3:19])[C:24]=2[C:32]([O:34][CH2:35][CH3:36])=[O:33])[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:7][CH:6]=1

Participants

3

Reactant 2

HCID 6619014HCID 6619014, compoundHCID 54458563HCID 54458563, compound

Product 1

HCID 67594329HCID 67594329, compoundYield 81.3%

Procedure

Substantially the same procedure as in Reference Example 5 was repeated using 4-(2-chloroethoxy)benzhydrol (17.66 g, 67.2 mmol) and ethyl 1-(2-dimethylaminoethyl)indole-2-carboxylate (19.2 g, 73.9 mmol) to give 27.6 g (yield: 81%) of the title compound.

Sources & evidence

ORD record
ord-d8464ef68567435083d823e204f21909
Source dataset
uspto-grants-1999_04
Patent number
US05891902

Reaction notes

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