反应详情

温度

150 °C

A mixture of 1-(2-bromo-ethyl)-4-nitro-benzene (86.9 mmoles) and 2-amino-ethanol (869 mmoles) is heated at 150° C. under microwave activation for 10 minutes. The reaction mixture is evaporated to dryness and the residue obtained is purified on silica gel (SiO2; gradient DCM/MeOH) to yield the title product, which is used directly in the next Step.

1. customThe reaction mixture is evaporated to dryness
2. customthe residue obtained
3. customis purified on silica gel (SiO2; gradient DCM/MeOH)