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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 443237Generated: October 29, 2026

Hydrochloric Acid → HCID 70204643, compound

https://huagongshe.com/reaction/443237

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 70204515HCID 70204515—
SolventEthyl AcetateHCID 8857—
ProductHCID 70204643HCID 70204643—

Reaction Conditions

Temperature0 °C

Reaction Steps

To a solution of trans -N-t-butoxycarbonyl-4-(3-methylphenyl)-3 hydroxypiperidine, (0.20 g, 0.12 mmol) in EtOAc (50 ml) at 0° C. was bubbled HCl gas until saturated. The reaction was stirred at 0° C. for 10 min and then the solvent evaporated in vacuo to afford the product as a white foam.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05891889
Source datasetuspto-grants-1999_04
ORD IDord-a3ef14bcb8cb464686fee2bc2b850dd1
Source noteuspto-grants-1999_04