反应详情

The product from Step C was dissolved in methanol and 5% aqueous sodium hydroxide added. After 1 h, methanol was removed in vacuo, and the residue partitioned between ethyl acetate and 10% aqueous HCl. The organic layer was washed with saturated brine, and dried over MgSO4. Filtration and concentration provided the title compound.

1. custommethanol was removed in vacuo
2. customthe residue partitioned between ethyl acetate and 10% aqueous HCl
3. washThe organic layer was washed with saturated brine
4. dry with materialdried over MgSO4
5. filtrationFiltration and concentration