Phosgene → 4-Phenoxymethylphenyl isocyanate

Participants

Reaction Steps

A solution of 4-phenoxymethylaniline (10 g) in toluene (100 ml) was added dropwise to a solution of phosgene (20 g) in toluene (100 ml) at 10° to 20° C. The mixture was gradually heated and refluxed for 30 minutes. Thereafter, the reaction mixture was cooled to room temperature, and the solvent was evaporated under reduced pressure to give 7 g of 4-phenoxymethylphenyl isocyanate. M.P., 56°-57° C.

Provenance & Evidence