反应详情

In 70 ml of 95% ethanol was dissolved 7.4 g of 1,1-diethoxy-6,10-dimethyl-2-oxo-5,9-undecadien, and the resulting solution was, after addition of 1.7 g of selenium oxide, refluxed for 15 minutes. The ethanol was removed by evaporation, and the residue was, after addition of water, extracted with ether. The ethereal extract was washed with an aqueous sodium hydrogencarbonate solution and dried. The solvent was then removed by evaporation to leave an oil, and the oil was purified by the silica gel column chromatography to yield 3.0 g of the desired product.

1. temperaturerefluxed for 15 minutes
2. customThe ethanol was removed by evaporation
3. additionafter addition of water
4. extractionextracted with ether
5. extractionThe ethereal extract
6. washwas washed with an aqueous sodium hydrogencarbonate solution
7. customdried
8. customThe solvent was then removed by evaporation
9. customto leave an oil
10. customthe oil was purified by the silica gel column chromatography