Hydrochloric Acid → HCID 15572411, compound

Participants

Reaction Steps

To the solution of 1.62 g of 2-(2-aminopropyl)-5-pyridinol hydrochloride in 50 ml of methanol, 0.83 g of n-hexanal are added, followed by 1.75 g of sodium cyanoborohydride, and the mixture is stirred at room temperature for 3 days. The pH thereof is first adjusted to 1 by the addition of 5 N ethereal hydrogen chloride, and then to 8 by the addition of solid sodium bicarbonate. The mixture is filtered, evaported and the residue triturated with isopropanol, to yield the oily 2-(2-n-hexylaminopropyl)-5-pyridinol, showing peaks in the mass-spectrum at 151, 128 and 109 m/e.

Provenance & Evidence