Benzyl chloroformate → HCID 54532864, compound

Participants

Reaction Steps

The starting material is prepared as follows: To the solution of 0.5 g of 2-(2-aminopropyl)-5-pyridinol, 10 ml of methylene chloride and 10 ml of saturated aqueous sodium bicarbonate, 1.04 g of benzyl chloroformate are added while stirring at room temperature. After 12 hours the organic phase is separated, dried, evaporated and the residue crystallized from diethyl ether-hexane, to yield the bis-carbobenzyloxy-2-(2-aminopropyl)-5-pyridinol melting at 63°-65°.

Provenance & Evidence