反应详情

In this preparation 42 g of 2-chloropropionyl chloride and 27.8 g aminoacetonitrile hydrochloride were admixed with 100 ml of trichloroethylene and stirred at reflux for 5 hours. The reaction mixture was then filtered and the filtrate was distilled to remove the solvent affording 42.6 g of an oily 2-chloro-N-cyanomethylpropionamide product.

1. temperatureat reflux for 5 hours
2. filtrationThe reaction mixture was then filtered
3. distillationthe filtrate was distilled
4. customto remove the solvent