Propionic Acid → HCID 13018769, compound

Participants

Reaction Steps

The experiment of Example 1A was repeated in all essential details except that p-bromobenzenethiol, 3-aminopropanol and propionic acid are the reactants. There is obtained N-[3-(p-bromophenylthio)propyl]propionamide, m.p. 64°-65.5°. The nmr spectrum was consistent with the proposed structure. The compound, which was designated P-2172, was ineffective against eight species of bacterium and one species of fungi (Candida albicans), but the MIC for three species of fungi was 50-1000 and is thus effective for controlling their growth.

Provenance & Evidence