Benzoyl isocyanate → N-(2-Cyano-6-methylphenylcarbamoyl)benzamide

HRID 44350Notes

Reaction equation

HRID 44350 reaction equation
[NH2:1][C:2]1[C:9]([CH3:10])=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[C:11]([N:19]=[C:20]=[O:21])(=[O:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[C:4]([C:3]1[CH:6]=[CH:7][CH:8]=[C:9]([CH3:10])[C:2]=1[NH:1][C:20]([NH:19][C:11](=[O:18])[C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)=[O:21])#[N:5]

Participants

3

Reactant 2

HCID 78210Benzoyl isocyanateHCID 108554942-Amino-3-methylbenzonitrile

Product 1

HCID 57456913N-(2-Cyano-6-methylphenylcarbamoyl)benzamide

Procedure

Prepared as in Example 1a from 2-amino-3-methylbenzonitrile (Example 15b) and benzoyl isocyanate as a white powder (186 mg, 67%). MS 280 (MH+).

Sources & evidence

ORD record
ord-24756ad5133c46598737c8a0970479d8
Source dataset
uspto-grants-2013_09
Patent number
US08541421B2

Reaction notes

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