反应详情

A mixture of 1.5 g. of 3-chloro-6-(3-pyridyl)pyridazine and 0.96 g. of formic acid hydrazide in 50 ml. of n-butyl alcohol is refluxed for 48 hours. The reaction mixture is concentrated, partitioned and crystallized as described in Example 1 to afford 1.0 g. of the product of the Example as a cream colored solid, m.p. 199°-200°.

1. additionA mixture of 1.5 g
2. concentrationThe reaction mixture is concentrated
3. custompartitioned
4. customcrystallized
5. customto afford 1.0 g