反应详情

N,N-di-(2,3-dihydroxypropyl)trimethylenediamine (11.1 g., 0.05 mole) is dissolved in 125 ml. of methanol and heated under reflux with agitation. Glycidol (3.7 g., 0.05 mole) is added dropwise over a period of 1.5 hour and the solution mixed an additional hour at 60° C.-80° C. The methyl alcohol and other volatiles are removed by stripping under reduced pressure to leave the product suitable for use in the next steps.

1. temperatureunder reflux with agitation
2. additionthe solution mixed an additional hour at 60° C.-80° C
3. customThe methyl alcohol and other volatiles are removed
4. customto leave the product suitable for use in the next steps