Pyridine → HCID 86737680, compound

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Reaction Steps

A mixture of 3.0 g. of 2-chloro-6-hydrazinopyridine (prepared in Example 1), 1.8 g. of pyridine and 50 ml. of methylene chloride is cooled to 0° C. in a ice bath, then a solution of 3.23 g. of dichloroacetyl chloride in 10 ml. of methylene chloride is added dropwise with stirring. The reaction mixture is stirred for 2 hours, then the fine precipitate is collected and rinsed with ice-cold methylene chloride and dried to provide 4.0 g. of the product of the Example m.p. 198°-200° C.

Provenance & Evidence