Pyridine → HCID 86737685, compound

Participants

Reaction Steps

A mixture of 2.1 g. of 2-chloro-6-hydrazinopyridine (prepared in Example 1), 1.25 g. of pyridine and 50 ml. of methylene chloride is cooled to 10° C. and is treated with 2.75 g. of 2-bromopropionyl chloride in 5 ml. of methylene chloride according to the procedure of Example 2. After a heavy precipitate forms the ice bath is removed and the reaction mixture is stirred at room temperature for 1/2 hour. The precipitate is collected and washed with methylene chloride to provide 2.6 g. of the product of the Example as a colorless solid m.p. 184° C.

Provenance & Evidence