Acetic Anhydride → HCID 19834543, compound

HRID 443592Notes

Reaction equation

HRID 443592 reaction equation
[NH:1]([C:8]1[C:12]([C:13]([O:15][CH3:16])=[O:14])=[C:11]([CH3:17])[NH:10][N:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:18](OC(=O)C)(=[O:20])[CH3:19]>>[C:18]([N:10]1[C:11]([CH3:17])=[C:12]([C:13]([O:15][CH3:16])=[O:14])[C:8]([NH:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[N:9]1)(=[O:20])[CH3:19]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 19834564HCID 19834564, compound

Product 1

HCID 19834543HCID 19834543, compound

Procedure

23 g of 3-anilino-4-methoxycarbonyl-5-methylpyrazole is dissolved in 51 g of acetic anhydride and brought to the boil. After 15 minutes' boiling the mixture is allowed to cool, poured into ice water and stirred for 30 minutes. The solid which separates is isolated and recrystallized from methanol; m.p. 115°-116° C.

Workup

  1. temperatureto cool
  2. customThe solid which separates is isolated
  3. customrecrystallized from methanol

Sources & evidence

ORD record
ord-04a0540a081a4e34942ee26cfa3dff2a
Source dataset
uspto-grants-1981_04
Patent number
US04260775

Reaction notes

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