反应详情

A mixture of 18.7 g. of 2-(2-naphthyloxy)ethanol O-methanesulfonate and 23.6 g. of ethyl p-aminobenzoate is heated in 300 ml. of hexamethylphosphoramide at 110° C. for 16 hours. The mixture is cooled, diluted with water and worked up as described in Example 3 to give the crystalline product. Recrystallization from ethanol gives crystals, m.p. 158°-162° C.

1. additionA mixture of 18.7 g
2. temperatureThe mixture is cooled
3. customto give the crystalline product
4. customRecrystallization from ethanol
5. customgives crystals, m.p. 158°-162° C.