HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzocaine → HCID 23468277, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzocaine | HCID 2337 | — |
| Reactant | Hexamethylphosphoramide | HCID 12679 | — |
| Reactant | HCID 23468299 | HCID 23468299 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 23468277 | HCID 23468277 | — |
Reaction Steps
The solution of 7.0 g. of 2-(4-bromo-1-naphthyloxy)ethyl bromide and 7.9 g. of ethyl 4-aminobenzoate in 50 ml. of hexamethylphosphoramide is heated for 18 hours, then cooled and diluted with 50 ml. of water. The precipitate is collected and crystallized from 200 ml. of methylcyclohexane and then from 100 ml. of ethanol, m.p. 126°-127° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04260816 |
| Source dataset | uspto-grants-1981_04 |
| ORD ID | ord-e5f5bf07302d437f9c5c6454e5170c1f |
| Source note | uspto-grants-1981_04 |