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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 443711Generated: October 30, 2026

Hydrochloric Acid → HCID 12437432, compound

https://huagongshe.com/reaction/443711

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium HydroxideHCID 14798—
ReactantHCID 12437412HCID 12437412—
ReactantHCID 12437450HCID 12437450—
ProductHCID 12437432HCID 12437432—

Reaction Steps

Dimethyl 3-(m-chlorophenyl)-4,5-isothiazoledicarboxylate (14.51 g, 0.0504 mol) was hydrolyzed as given above with NaOH (10.08 g, 0.252 mol) and then acidified with HCl. The purified yellow solid had m.p. 185°-6° with decomposition (rapid heating of the sample produced normal decomposition in this temperature range; slow heating caused a color change to red and m.p. 217.5°-218.5° with decomposition. Infrared of material heated slowly to 190° showed that it was 3-(m-chlorophenyl)-4-isothiazolecarboxylic acid).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04261728
Source datasetuspto-grants-1981_04
ORD IDord-3a4387bb1ba84a26bb0201d30de74188
Source noteuspto-grants-1981_04