Sodium Hydroxide → HCID 12724768, compound

HRID 443853Notes

Reaction equation

HRID 443853 reaction equation
[CH3:1][N:2]1[C:11]2[CH:10]=[CH:9][C:8]([CH3:12])=[CH:7][C:6]=2[C:5](=[O:13])[N:4]2[N:14]=[C:15]([C:17]([O:19]CC)=[O:18])[CH:16]=[C:3]12.[OH-].[Na+]>CO>[CH3:1][N:2]1[C:11]2[CH:10]=[CH:9][C:8]([CH3:12])=[CH:7][C:6]=2[C:5](=[O:13])[N:4]2[N:14]=[C:15]([C:17]([OH:19])=[O:18])[CH:16]=[C:3]12

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 12724763HCID 12724763, compound

Product 1

HCID 12724768HCID 12724768, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

From 3.5 g of 4,9-dihydro-4,7-dimethyl-9-oxo-pyrazolo[5,1-b]quinazoline-2-carboxylic acid, ethyl ester, 50 ml of 1 N aqueous sodium hydroxide and 200 ml of methanol, following the procedure of Example 14, there is obtained 4,9-dihydro-4,7-dimethyl-9-oxo-pyrazolo[5,1-b]quinazoline-2-carboxylic acid; mp 269° C., after crystallization from dimethylformamide/ ethanol.

Sources & evidence

ORD record
ord-c78049a320334c78b5e45bf35ce4618a
Source dataset
uspto-grants-1981_04
Patent number
US04261997

Reaction notes

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