5-Fluoroisatoic anhydride → 6-Fluoro-1-methyl-2H-3,1-benzoxazine-2,4(1H)-dione

HRID 443861Notes

Reaction equation

HRID 443861 reaction equation
[F:1][C:2]1[CH:13]=[C:6]2[C:7]([O:9][C:10](=[O:12])[NH:11][C:5]2=[CH:4][CH:3]=1)=[O:8].[CH3:14]C1C=C2C(OC(=O)NC2=CC=1)=O>>[F:1][C:2]1[CH:13]=[C:6]2[C:7]([O:9][C:10](=[O:12])[N:11]([CH3:14])[C:5]2=[CH:4][CH:3]=1)=[O:8]

Participants

3

Reactant 2

HCID 2885605-Fluoroisatoic anhydrideHCID 2944785-Methylisatoic anhydride

Product 1

HCID 127132306-Fluoro-1-methyl-2H-3,1-benzoxazine-2,4(1H)-dione

Procedure

By substituting 27 g of 5-fluoroisatoic anhydride for the 5-methylisatoic anhydride Preparative Example 13, there is obtained 5-fluoro-N-methylisatoic anhydride; mp 150°-155° C.

Sources & evidence

ORD record
ord-3a093e1feb074daf92289f199a5cd7dd
Source dataset
uspto-grants-1981_04
Patent number
US04261997

Reaction notes

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