Ethyl chloroformate → HCID 178473355, compound

Participants

Reaction Steps

A mixture of 2-(2,4-dichlorophenylimino)imidazolidine (9.2 g.), sodium hydride (1.3 g. as 80% dispersion in oil) and tetrahydrofuran (65 ml.) was stirred and heated under reflux for 1 hour. The mixture was cooled and a solution of ethyl chloroformate (4.8 g.) in tetrahydrofuran (20 ml.) was added dropwise. The mixture was then stirred and heated under reflux for a further three hours. The mixture was cooled and then poured onto an ice-water mixture to give a solid which was dried over phosphorus pentoxide. Recrystallisation with charcoal from isopropanol gave 2-(2,4-dichlorophenylimino)-1-ethoxycarbonylimidazolidine, m.p. 138°-139° C.

Provenance & Evidence