反应详情

A mixture of 17 parts (3-amino-4-chlorophenyl) phenylmethanone, 9.5 parts of carbonothioic dichloride and 200 parts of 1,4-dioxane is stirred and refluxed for 15 minutes. The reaction mixture is evaporated and the oily residue is crystallized from 2,2'-oxybispropane. The product is filtered off and dried, yielding 17 parts (85%) of (4-chloro-3-isothiocyanatophenyl)phenylmethanone; mp. 96.7° C.

1. temperaturerefluxed for 15 minutes
2. customThe reaction mixture is evaporated
3. customthe oily residue is crystallized from 2,2'-oxybispropane
4. filtrationThe product is filtered off
5. customdried