HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boc-Tyr-(D)Ala-Gly-OBzl → Boc-tyr-D-ala-gly-OH
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boc-Tyr-(D)Ala-Gly-OBzl | HCID 15567201 | — |
| Solvent | Palladium | HCID 23938 | — |
| Solvent | Methanol--water (1/1) | HCID 22242641 | — |
| Product | Boc-tyr-D-ala-gly-OH | HCID 7272028 | — |
Reaction Steps
12 g of Boc-Tyr-(D)Ala-Gly-OBzl are dissolved in a mixture of methanol/H2O (9:1) and hydrogenated in the presence of Pd-C at normal pressure and room temperature. The mixture is fitered off from the catalyst, reduced in volume and crystallised from methanol/CH2CL2 /ether. Decomp. 110°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04261888 |
| Source dataset | uspto-grants-1981_04 |
| ORD ID | ord-89b3667015f14726b34ac4f3d39bd952 |
| Source note | uspto-grants-1981_04 |