Sodium Hydroxide → HCID 12878302, compound

Participants

Reaction Steps

According to the method described in Example 25 (b), the reaction was carried out by using 0.13 ml of bromine and 0.74 g of the carboxylic acid which was prepared from 0.80 g of ethyl 3-hydroxy-3-methyl-8-(p-benzyloxyphenyl)-4-octenoate, 8 ml of ethanol and 1 ml of 4 N sodium hydroxide, and the product was recrystallized from ethyl ether to give 0.32 g of the desired compound melting at 100°-101° C.

Provenance & Evidence