Thiourea → HCID 178419248, compound

HRID 443977Notes

Reaction equation

HRID 443977 reaction equation
[BrH:1].[Br:2][CH2:3][C:4]1[N:5]=[CH:6][NH:7][C:8]=1[CH3:9].[NH2:10][C:11]([NH2:13])=[S:12]>CCO>[BrH:2].[BrH:1].[CH3:9][C:8]1[N:7]=[CH:6][NH:5][C:4]=1[CH2:3][S:12][C:11](=[NH:10])[NH2:13]

Participants

4

Reactant 2

HCID 2723790ThioureaHCID 12790399HCID 12790399, compound

Product 1

HCID 178419248HCID 178419248, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 12.8 g of 4-bromomethyl-5-methyl imidazole hydrobromide and 4 g. of thiourea in 200 ml. of EtOH is heated at reflux for 3 hr., cooled and the product is filtered off to give the title compound, m.p. 130°-132° C. (dec.).

Workup

  1. temperatureat reflux for 3 hr
  2. temperature, cooled
  3. filtrationthe product is filtered off

Sources & evidence

ORD record
ord-33c29b640c624021810a2fb81b4f22f5
Source dataset
uspto-grants-1981_04
Patent number
US04262125

Reaction notes

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