Diethyl Ether → HCID 53767454, compound

Participants

Reaction Steps

Propionyl chloride (5.1 g) was added dropwise to 2-(2-hydroxy-5-cyanophenyl)-2-methyl-1-propanol (5 g) prepared as in Example 26 and triethylamine (5.5 g) in diethyl ether (50 ml) with stirring and cooling. After stirring for 3 hours at room temperature, the mixture was washed twice with water, dried over magnesium sulphate and run down, giving 6.5 g of crude product. After filtration through alumina in toluene, 5.3 g of title product were obtained as a viscous oil.

Provenance & Evidence