Methyl Acrylate → HCID 54430997, compound

Participants

Reaction Steps

Charged in a stainless steel autoclave having an inner capacity of 200 ml were 5.5 g of 2-acetylfuran, 1.72 g of methyl acrylate, 0.038 g of Rh4 (CO)12 and 50 ml of tetrahydrofuran, followed by supply of carbon monoxide under 30 kg/cm2. Reaction was carried out at 220° C. for 7 hours. Tetrahydrofuran and unreacted 2-acetylfuran were removed from the obtained light brown solution by distillation under reduced pressure, and the residue was separated and purified by silica gel column chromatography. From a fraction eluted with methylene chloride was obtained 0.62 g of methyl β-(5-acetyl-2-furyl)acrylate (3) (the yield was 16%).

Provenance & Evidence