Ethanol → HCID 13013935, compound

Participants

Reaction Steps

Stir a mixture 2.04 gm (6.77 mmole) of the ester from Example 17. 2.24 gm (20 mmole) of 85% aqueous potassium hydroxide, 11 ml of water, 55 ml of ethanol and 5.5 ml of dioxane under argon at room temperature for 1 hour. Evaporate to a syrup and dilute with 25 ml of water. Charcoal and filter twice. Acidify with acetic acid. Separate the precipitate by filtration, wash with water and dry to obtain the title product (m.p. 302° C. dec.).

Provenance & Evidence