10,11-Dihydro-11-oxodibenzo[b,f][1,4]thiazepin-3-carboxylic acid → HCID 23464472, compound

HRID 444164Notes

Reaction equation

HRID 444164 reaction equation
[O:1]=[C:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[S:6][C:5]2[CH:13]=[C:14]([C:17]([OH:19])=O)[CH:15]=[CH:16][C:4]=2[NH:3]1.O=C1C2C=CC(C(O)=O)=CC=2SC2C=CC=CC=2[NH:22]1>>[O:1]=[C:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[S:6][C:5]2[CH:13]=[C:14]([C:17]([NH2:22])=[O:19])[CH:15]=[CH:16][C:4]=2[NH:3]1

Participants

3

Reactant 2

HCID 1301392310,11-Dihydro-11-oxodibenzo[b,f][1,4]thiazepin-3-carboxylic acidHCID 13013939HCID 13013939, compound

Product 1

HCID 23464472HCID 23464472, compound

Procedure

In a similar manner, substituting 10,11-dihydro-11-oxodibenzo[b,f][1,4]thiazepin-7-carboxylic acid for the 10,11-dihydro-11-oxodibenzo[b,f][1,4]thiazepin-3-carboxylic acid in Step A, there is obtained 10,11-dihydro-11-oxodibenzo[b,f][1,4]thiazepin-7-carboxamide. Carboxamides of 10,11-dihydrodibenzo[b,f][1,4]thiazepin-3(or 7)-carboxylic acid or dibenzo[b,f][1,4]thiazepin-3(or 7)-carboxylic acid are prepared by the process of Example 33, by substituting the desired 3(or 7) carboxylic acid for the starting material of Step A.

Sources & evidence

ORD record
ord-0c7bbb31e2df401e9872cb0b8df88883
Source dataset
uspto-grants-1981_04
Patent number
US04263207

Reaction notes

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