Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetone → 4-[2-(4-Methylphenyl)ethoxy]aniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetone | HCID 180 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 1-Methyl-4-[2-(4-nitrophenoxy)ethyl]benzene | HCID 5142926 | — |
| 반응물 | Sulfur | HCID 5362487 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4-[2-(4-Methylphenyl)ethoxy]aniline | HCID 13017656 | 96.9% |
반응 단계
4-[2-(4-Methylphenyl)ethoxy]nitrobenzene (VI) (5.14 g, 0.02 mole), sodium hydroxide powder (3.0 g) and sulfur (1.6 g, 0.05 mole) were added to a mixture of acetone (20 ml) and methanol (20 ml), followed by heating under reflux for 5 hours. After cooling, the reaction mixture was diluted with water, extracted with ether and treated in the same manner as in Example 18 to obtain 4.4 g of 4-[2-(4-methylphenyl)ethoxy]aniline (V) (yield, 96.9%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04263219 |
| 출처 데이터셋 | uspto-grants-1981_04 |
| ORD ID | ord-23f8e7c49fbb4f44bf87f4417a43576d |
| 출처 메모 | uspto-grants-1981_04 |