HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 86737701, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 2-Bromo-4'-methylacetophenone | HCID 69272 | — |
| Reactant | 4-NITROPHENOL SODIUM SALT DIHYDRATE | HCID 2735104 | — |
| Product | HCID 86737701 | HCID 86737701 | 62.3% |
Reaction Steps
4-Methylphenacyl bromide (XVI: X=Br) (63 g, 0.296 mole), 4-nitrophenol (XI) (42.4 g, 0.305 mole) and potassium hydroxide (22.5 g, 0.4 mole) were added to methanol (300 ml), and the mixture was heated under reflux for 4 hours. Thereafter, the reaction mixture was treated in the same manner as in Example 29 to obtain 50.0 g of 4-methyl-α-(4-nitrophenoxy)acetophenone (XII) (yield, 62.3%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04263219 |
| Source dataset | uspto-grants-1981_04 |
| ORD ID | ord-586e7695ced549b58b164a5d43582fe0 |
| Source note | uspto-grants-1981_04 |