Ethanol → HCID 13017653, compound

Participants

Reaction Steps

10% Palladium-carbon (0.1 g) was added to a solution of 4-methyl-α-(4-acetamidophenoxy)acetophenone (XIII: R=CH3) (2.83 g, 0.01 mole) in ethanol (50 ml), and catalytic reduction was carried out at 25° C. for 2 hours during which 290 ml of hydrogen was absorbed. After removing the catalyst by filtration, after-treatment was carried out in the same manner as in Example 35 to obtain 2.55 g of β-(4-acetamidophenoxy)-α-(4-methylphenyl)ethyl alcohol (XIV: R=CH3) as white crystals (yield, 89.5%).

Provenance & Evidence